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Home › Dataset Library › Gene expression profiles of Hodgkin’s lymphoma cell lines with different sensitivity to cytotoxic drugs

Dataset: Gene expression profiles of Hodgkin’s lymphoma cell lines with different sensitivity to cytotoxic drugs

By using high-density DNA microarrays, we analyzed the gene-expression profile of Hodgkin's lymphoma cell lines. Furthermore, we tested...

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By using high-density DNA microarrays, we analyzed the gene-expression profile of Hodgkin's lymphoma cell lines. Furthermore, we tested the sensitivity of these cell lines for cytotoxic drugs (cisplatin, etoposide, melphalan) and compared the gene-expression profile of chemotherapy-resistant and -sensitive cell lines. Staege et al., Exp Hematol 2008;36:886-896 RNA was extracted from established Hodgkin's lymphoma cell lines and hybridized with Affymetrix HG_U133A microarrays.

Species:
human

Samples:
6

Source:
E-GEOD-26325

PubMed:
18400362

Updated:
Dec.12, 2014

Registered:
Jun.19, 2014


Factors: (via ArrayExpress)
Sample CELL LINE CHEMOTHERAPY SENSITIVITY
GSM646536 Hodgkin’s lymphoma cell line L-1236 lowest sensitivity
GSM646535 Hodgkin’s lymphoma cell line L-540 highest sensitivity
GSM646534 Hodgkin’s lymphoma cell line HDLM-2 intermediate sensitivity
GSM646533 Hodgkin’s lymphoma cell line KM-H2 intermediate sensitivity
GSM646535 Hodgkin’s lymphoma cell line L-540 highest sensitivity
GSM646536 Hodgkin’s lymphoma cell line L-1236 lowest sensitivity

Tags

  • cell
  • hodgkin's lymphoma
  • lymphoma

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