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Home › Dataset Library › Expression data from control and ZNF145-overexpressing human mesenchymal stem cells (MSCs)

Dataset: Expression data from control and ZNF145-overexpressing human mesenchymal stem cells (MSCs)

ZNF145 is shown to be upregulated during three linage differentiation of MSCs especially in chondrogenesis. To understand the molecular...

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ZNF145 is shown to be upregulated during three linage differentiation of MSCs especially in chondrogenesis. To understand the molecular basis of ZNF145 underlying MSCs, targets of ZNF145 in MSCs are determined by microarray We used microarrays to detail the change in gene expression profile upon overexpression of ZNF145 compared with control in undifferentiated MSCs Control MSCs and ZNF145-overexpressing MSCs are processed for RNA extraction and hybridization on Affymetrix microarrays. To that end, we overexpressed ZNF145 in two patient-derived human MSCs.

Species:
human

Samples:
8

Source:
E-GEOD-26272

Updated:
Dec.12, 2014

Registered:
Sep.15, 2014


Factors: (via ArrayExpress)
Sample PATIENT GENOTYPE/VARIATION
GSM645185 1 control
GSM645185 1 control
GSM645187 1 ZNF145-overexpressin
GSM645187 1 ZNF145-overexpressin
GSM645189 2 control
GSM645189 2 control
GSM64519 2 ZNF145-overexpressin
GSM64519 2 ZNF145-overexpressin

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