{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "human", "factors": [{"GSM641483": {"CELL LINE": "MV4-11"}}, {"GSM641483": {"CELL LINE": "MV4-11"}}, {"GSM641483": {"CELL LINE": "MV4-11"}}, {"GSM641483": {"CELL LINE": "MV4-11"}}, {"GSM641483": {"CELL LINE": "MV4-11"}}, {"GSM641483": {"CELL LINE": "MV4-11"}}, {"GSM641483": {"CELL LINE": "MV4-11"}}, {"GSM641483": {"CELL LINE": "MV4-11"}}, {"GSM641483": {"CELL LINE": "MV4-11"}}, {"GSM641483": {"CELL LINE": "MV4-11"}}, {"GSM641483": {"CELL LINE": "MV4-11"}}, {"GSM641483": {"CELL LINE": "MV4-11"}}, {"GSM641495": {"CELL LINE": "MOLM-14"}}, {"GSM641495": {"CELL LINE": "MOLM-14"}}, {"GSM641495": {"CELL LINE": "MOLM-14"}}, {"GSM641495": {"CELL LINE": "MOLM-14"}}, {"GSM641495": {"CELL LINE": "MOLM-14"}}, {"GSM641495": {"CELL LINE": "MOLM-14"}}, {"GSM641495": {"CELL LINE": "MOLM-14"}}, {"GSM641495": {"CELL LINE": "MOLM-14"}}, {"GSM641495": {"CELL LINE": "MOLM-14"}}, {"GSM641495": {"CELL LINE": "MOLM-14"}}, {"GSM641495": {"CELL LINE": "MOLM-14"}}, {"GSM641495": {"CELL LINE": "MOLM-14"}}], "id": 3894, "pop_total": 0, "platform": 4, "summary_wrapped": "For the microarray experiments, MV4-11 and MOLM-14 cells were treated with DMSO control, ABT-869 3 nM, SAHA 6 \uf06dM and combination therapy...", "pubmed_id": 21589872, "geo_gse_id": "E-GEOD-26114", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 24, "tags": [], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "combination-of-abt-869-with-saha-on-aml-with-flt3", "geo_id_plat": "E-GEOD-26114_A-AFFY-44", "name": "Combination of ABT-869 with SAHA on AML with FLT3-ITD", "created": "Sep.15, 2014", "summary": "For the microarray experiments, MV4-11 and MOLM-14 cells were treated with DMSO control, ABT-869 3 nM, SAHA 6 \uf06dM and combination therapy for 24 hours. Cells were then washed in PBS and high-quality total RNA was extracted RNeasy Midi Kit, according to the manufacturer\u2019s instruction (Qiagen, Valencia, USA). RNA quantity, quality, and purity were assessed with the use of the RNA 6000 Nano assay on the Agilent 2100 Bioanalyzer (Agilent Technologies, Santa Clara CA, USA). Gene expression profiling was performed using Affymetric U133plus2.0 gene chip (Affymetrix, Santa Clara, CA, USA) according to the manufacturer\u2019s protocol. MV4-11 and MOLM-14 cells were treated with DMSO control, ABT-869, SAHA or combination therapy for 24 hours.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-26114", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-26114/samples/"}