{"platform": 8, "owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM625452": {"GENOTYPE": "WT"}}, {"GSM625452": {"GENOTYPE": "WT"}}, {"GSM625452": {"GENOTYPE": "WT"}}, {"GSM625452": {"GENOTYPE": "WT"}}, {"GSM625452": {"GENOTYPE": "WT"}}, {"GSM625457": {"GENOTYPE": "NFkBp65-/-"}}, {"GSM625457": {"GENOTYPE": "NFkBp65-/-"}}, {"GSM625457": {"GENOTYPE": "NFkBp65-/-"}}, {"GSM625457": {"GENOTYPE": "NFkBp65-/-"}}, {"GSM625457": {"GENOTYPE": "NFkBp65-/-"}}], "id": 8519, "ownerprofile_id": "arrayexpress_sid", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-25469", "summary_wrapped": "Toxoplasma strains have been shown to modulate host cell transcription.  We have found a type II Toxoplasma gene, GRA15, which activates...", "pubmed_id": 21199955, "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 10, "tags": ["cell", "genome"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-from-wt-or-p65-mouse-embryonic-fib", "geo_id_plat": "E-GEOD-25469_A-AFFY-36", "name": "Expression data from WT or p65-/- mouse embryonic fibroblasts (MEFs) infected with Toxoplasma gondii.", "created": "Nov.24, 2014", "summary": "Toxoplasma strains have been shown to modulate host cell transcription.  We have found a type II Toxoplasma gene, GRA15, which activates the nuclear translocation of the NF-kappaB p65 transcription factor. We used microarrays to determine how GRA15II modulates host cell transcription, and whether this transcription is dependent on the p65 transcription factor. WT or p65-/- MEFs were infected with type I (RH), type I GRA15II (RH GRA15II), type II (Pru), or type II GRA15KO (Pru GRA15KO) parasites for 18-24 hours. Total RNA was isolated and hybridized to Affymetrix GeneChip Human Genome U133A 2.0 arrays.", "geo_gse_id": "E-GEOD-25469", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-25469/samples/"}