{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "mouse", "factors": [{"GSM610739": {"GENOTYPE/VARIATION": "BCL6 WT", "AGENT": "untreated"}}, {"GSM610739": {"GENOTYPE/VARIATION": "BCL6 WT", "AGENT": "untreated"}}, {"GSM610776": {"GENOTYPE/VARIATION": "BCL6 WT", "AGENT": "imatinib"}}, {"GSM610776": {"GENOTYPE/VARIATION": "BCL6 WT", "AGENT": "imatinib"}}, {"GSM610842": {"GENOTYPE/VARIATION": "BCL6 WT", "AGENT": "Imatinib/RI-BPI"}}, {"GSM610842": {"GENOTYPE/VARIATION": "BCL6 WT", "AGENT": "Imatinib/RI-BPI"}}, {"GSM610858": {"GENOTYPE/VARIATION": "BCL6 KO", "AGENT": "untreated"}}, {"GSM610858": {"GENOTYPE/VARIATION": "BCL6 KO", "AGENT": "untreated"}}, {"GSM610860": {"GENOTYPE/VARIATION": "BCL6 KO", "AGENT": "imatinib"}}, {"GSM610860": {"GENOTYPE/VARIATION": "BCL6 KO", "AGENT": "imatinib"}}], "id": 6248, "pop_total": 0, "platform": 6, "summary_wrapped": "To identify differences in the gene regulation between BCL6+/+ and BCL6-/- CML cells a gene expression analysis has been performed. We...", "geo_gse_id": "E-GEOD-24813", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 10, "tags": ["cml"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "gene-expression-data-of-bcr-abl1-transformed-myelo", "geo_id_plat": "E-GEOD-24813_A-AFFY-45", "name": "Gene expression data of BCR-ABL1 transformed myeloid cells from BCL6 wild-type and BCL6 knockout mice treated with and without Imatinib and RI-BPI", "created": "Nov.11, 2014", "summary": "To identify differences in the gene regulation between BCL6+/+ and BCL6-/- CML cells a gene expression analysis has been performed. We investigated the gene expression pattern in BCL6+/+ cells in the presence or absence of Imatinib and a combination of Imatinib and RI-BPI (a novel retro-inverso BCL6 peptide inhibitor). In BCL6-/- CML cells, we investigated the gene expression pattern in the presence or absence of Imatinib.  BCR-ABL1 transformed myeloid cells from BCL6+/+ mice were cultured in the presence or absence of 10\u00b5M Imatinib or 10\u00b5M Imatinib and 20\u00b5M RI-BPI for 16 hours. BCR-ABL1 transformed myeloid cells from BCL6-/- mice were cultured in the presence or absence of 10\u00b5M Imatinib. Two samples for each condition were processed.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24813", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24813/samples/"}