{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "mouse", "factors": [{"GSM610470": {"MALIGNANT POTENTIAL": "non-malignant"}}, {"GSM610470": {"MALIGNANT POTENTIAL": "non-malignant"}}, {"GSM610470": {"MALIGNANT POTENTIAL": "non-malignant"}}, {"GSM610473": {"MALIGNANT POTENTIAL": "intermediate"}}, {"GSM610473": {"MALIGNANT POTENTIAL": "intermediate"}}, {"GSM610473": {"MALIGNANT POTENTIAL": "intermediate"}}, {"GSM610476": {"MALIGNANT POTENTIAL": "malignant"}}, {"GSM610476": {"MALIGNANT POTENTIAL": "malignant"}}, {"GSM610476": {"MALIGNANT POTENTIAL": "malignant"}}], "id": 6246, "pop_total": 0, "platform": 6, "summary_wrapped": "Ovarian cancer is one of the most deadly cancers accounting for only 3% of diagnosed cancers, but is the fifth leading cause of cancer...", "geo_gse_id": "E-GEOD-24789", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 9, "tags": ["cancer", "cell", "intermediate", "ovarian cancer", "surface"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-from-mouse-ovarian-surface-epithel", "geo_id_plat": "E-GEOD-24789_A-AFFY-45", "name": "Expression data from mouse ovarian surface epithelium cells at different stages of malignancy", "created": "Nov.11, 2014", "summary": "Ovarian cancer is one of the most deadly cancers accounting for only 3% of diagnosed cancers, but is the fifth leading cause of cancer deaths among woman; however, the progression of ovarian cancer is poorly understood.  To study and further understand the early events that lead to epithelial derived ovarian cancer, we previously developed a cell model of progressive ovarian cancer. Mouse ovarian surface epithelial (MOSE) cells have undergone spontaneous transformation in cell culture and represent pre-neoplastic, non-tumorigenic to an aggressive malignant phenotype. Microarray analysis was performed with RNA isolated from different stages of MOSE cells to examine changes in gene expression as MOSE cells transition from a pre-neoplastic to a malignant state. RNA was isolated from MOSE early cell representing a pre-neoplastic, non-malignant stage, MOSE Intermediate cells representing a noeplastic, pre-invasive state, and MOSE Late cells representing a malignant, invasive stage.  Three biological replicates were used to take into account variations within the heterogeneous cultures.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24789", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24789/samples/"}