3ArrayExpress Uploader0human4.063.2female4.063.2female4.063.2female4.063.2female4.063.2female1.045.0male1.045.0male1.045.0male1.045.0male1.045.0male1.025.6female1.025.6female1.025.6female1.025.6female1.025.6female4.027.9female4.027.9female4.027.9female4.027.9female4.027.9female3.051.4female3.051.4female3.051.4female3.051.4female3.051.4female2.041.6female2.041.6female2.041.6female2.041.6female2.041.6female4.044.3female4.044.3female4.044.3female4.044.3female4.044.3female1.530.9male1.530.9male1.530.9male1.530.9male1.530.9male4.026.3female4.026.3female4.026.3female4.026.3female4.026.3female1.042.4male1.042.4male1.042.4male1.042.4male1.042.4male2.029.0male2.029.0male2.029.0male2.029.0male2.029.0male1.528.2female1.528.2female1.528.2female1.528.2female1.528.2female1.048.4female1.048.4female1.048.4female1.048.4female1.048.4female3.547.8female3.547.8female3.547.8female3.547.8female3.547.8female2.042.7female2.042.7female2.042.7female2.042.7female2.042.7female3.550.3female3.550.3female3.550.3female3.550.3female3.550.3female1.537.0male1.537.0male1.537.0male1.537.0male1.537.0male2.043.9female2.043.9female2.043.9female2.043.9female2.043.9female3.054.4male3.054.4male3.054.4male3.054.4male3.054.4male1.040.8male1.040.8male1.040.8male1.040.8male1.040.8male2.048.7female2.048.7female2.048.7female2.048.7female2.048.7female2.038.2female2.038.2female2.038.2female2.038.2female2.038.2female1.518.3male1.518.3male1.518.3male1.518.3male1.518.3male1.024.6female1.024.6female1.024.6female1.024.6female1.024.6female1.038.2male1.038.2male1.038.2male1.038.2male1.038.2male9659arrayexpress_sidhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24427The purpose of this study was to characterize the transcriptional effects induced by subcutaneous IFN-beta-1b treatment (Betaferon, 250...20136355/profile/8773/arrayexpressuploader0125genomemultiple sclerosisperipheralJan.17, 2015Falseexpression-data-of-multiple-sclerosis-patients-recE-GEOD-24427_A-AFFY-33Expression data of multiple sclerosis patients receiving Interferon-beta therapyJan.17, 2015The purpose of this study was to characterize the transcriptional effects induced by subcutaneous IFN-beta-1b treatment (Betaferon, 250 µg every other day) in patients with relapsing-remitting form of multiple sclerosis (MS). By using Affymetrix DNA microarrays, we obtained genome-wide expression profiles of peripheral blood mononuclear cells from 25 MS patients within the first two years of IFN-beta administration. EDTA blood samples were drawn from all patients immediately before first, second, month 1, 12, and 24 IFN-beta injection. Total RNA of Ficoll-isolated peripheral blood mononuclear cells from each sample was extracted, labelled and hybridized to Affymetrix Human Genome U133 A and B arrays to quantify the mRNA levels.E-GEOD-24427http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24427/samples/