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Home › Dataset Library › Gene expression profiling of four subpopulations in GBM

Dataset: Gene expression profiling of four subpopulations in GBM

GBM is a heterogenous brain tumor with hyperproliferation of endothelial cells. In order to understand the cellular mechanism of...

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GBM is a heterogenous brain tumor with hyperproliferation of endothelial cells. In order to understand the cellular mechanism of vasculogenesis in GBM, four fractions of cells are seperated. Microarray assays was performed to examine the potential lineage relationship and the signal pathways involved in determining the cell identity and function. Four subpopulation of cells were seperated from two independent GBM dissociates by FCAS assay based on the expression of membrane marker CD133 and CD144. Total RNA was extracted from freshly sorted cells without any culture.

Species:
human

Samples:
8

Source:
E-GEOD-24244

Updated:
Dec.12, 2014

Registered:
Sep.15, 2014


Factors: (via ArrayExpress)
Sample GENDER AGE CELL TYPE
GSM59549 male 43 y CD133+ cell
GSM595492 male 43 y CD144+ cell
GSM595493 male 43 y CD133+, CD144+ cell
GSM595494 male 43 y CD133-, CD144- cell
GSM595495 female 41 y CD133+ cell
GSM595496 female 41 y CD144+ cell
GSM595513 female 41 y CD133-, CD144- cell
GSM595514 female 41 y CD133+, CD144+ cell

Tags

  • brain
  • cell
  • gbm
  • membrane

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