<?xml version="1.0" encoding="ASCII"?>
<biogps><data><item key="owner">ArrayExpress Uploader</item><item key="pop_total">0</item><item key="species">mouse</item><item key="factors"><item><item key="GSM595109"><item key="GENOTYPE/VARIATION">wild type</item></item></item><item><item key="GSM595110"><item key="GENOTYPE/VARIATION">RASSF9-/-</item></item></item><item><item key="GSM595"><item key="GENOTYPE/VARIATION">RASSF9 -/-</item></item></item></item><item key="id">6213</item><item key="ownerprofile_id">arrayexpress_sid</item><item key="platform">6</item><item key="summary_wrapped">Mice with deficient expression of RASSF9 exhibit intriguing phenotypes of skin-related pathology, including abnormal thickening of the...</item><item key="geo_gse_id">E-GEOD-24190</item><item key="owner_profile">/profile/8773/arrayexpressuploader</item><item key="factor_count">1</item><item key="sample_count">3</item><item key="tags"><item>alopecia</item><item>epidermis</item><item>skin</item></item><item key="lastmodified">Dec.12, 2014</item><item key="is_default">False</item><item key="geo_gds_id"/><item key="slug">expression-data-from-keratinocytes-of-wt-and-rassf</item><item key="geo_id_plat">E-GEOD-24190_A-AFFY-45</item><item key="name">Expression data from keratinocytes of WT and RASSF9-/- mice</item><item key="created">Nov.11, 2014</item><item key="summary">Mice with deficient expression of RASSF9 exhibit intriguing phenotypes of skin-related pathology, including abnormal thickening of the epidermis, dysregulated proliferation of keratinocytes, and alopecia. To delineate the underlying mechanism, we profiled gene expression in keratinocytes of RASSF9-mutant mice to identify targets whose expressions were affected by RASSF9 gene deletion. Primary keratinocytes from neonatal ICR mice of wildtype control (WT) or homozygous RASSF9 deletion (RASSF9-/-) were harvested for RNA extraction and hybridization on Affymetrix microarrays. For WT, a single microarray hybridization was performed. For RASSF9-/-, one hybridization was performed for each of two independent samples.</item><item key="source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24190</item><item key="sample_source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24190/samples/</item></data></biogps>
