{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM595109": {"GENOTYPE/VARIATION": "wild type"}}, {"GSM595110": {"GENOTYPE/VARIATION": "RASSF9-/-"}}, {"GSM595": {"GENOTYPE/VARIATION": "RASSF9 -/-"}}], "id": 6213, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Mice with deficient expression of RASSF9 exhibit intriguing phenotypes of skin-related pathology, including abnormal thickening of the...", "geo_gse_id": "E-GEOD-24190", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 3, "tags": ["alopecia", "epidermis", "skin"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-24190_A-AFFY-45", "slug": "expression-data-from-keratinocytes-of-wt-and-rassf", "geo_gds_id": "", "name": "Expression data from keratinocytes of WT and RASSF9-/- mice", "created": "Nov.11, 2014", "summary": "Mice with deficient expression of RASSF9 exhibit intriguing phenotypes of skin-related pathology, including abnormal thickening of the epidermis, dysregulated proliferation of keratinocytes, and alopecia. To delineate the underlying mechanism, we profiled gene expression in keratinocytes of RASSF9-mutant mice to identify targets whose expressions were affected by RASSF9 gene deletion. Primary keratinocytes from neonatal ICR mice of wildtype control (WT) or homozygous RASSF9 deletion (RASSF9-/-) were harvested for RNA extraction and hybridization on Affymetrix microarrays. For WT, a single microarray hybridization was performed. For RASSF9-/-, one hybridization was performed for each of two independent samples.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24190", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24190/samples/"}