{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM593029": {"GENDER": "female", "AGE": 47, "CELL LINE": "SCC4", "TISSUE DERIVATION": "tongue", "HPV STATUS": "negative", "CELL TYPE": "head and neck squamous cell carcinoma (HNSCC)"}}, {"GSM593030": {"GENDER": "male", "AGE": 59, "CELL LINE": "SCC74A", "TISSUE DERIVATION": "tongue", "HPV STATUS": "negative", "CELL TYPE": "head and neck squamous cell carcinoma (HNSCC)"}}, {"GSM59303": {"GENDER": "male", "AGE": 53, "CELL LINE": "SCC47", "TISSUE DERIVATION": "tongue", "HPV STATUS": "positive", "CELL TYPE": "head and neck squamous cell carcinoma (HNSCC)"}}, {"GSM593032": {"GENDER": "female", "AGE": 43, "CELL LINE": "CaSki", "TISSUE DERIVATION": "cervix", "HPV STATUS": "positive", "CELL TYPE": "female genital squamous cell carcinoma"}}], "id": 3805, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Oncogenic human papillomaviruses (HPVs) are associated with nearly all carcinomas of the uterine cervix and have also become an...", "geo_gse_id": "E-GEOD-24089", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 6, "sample_count": 4, "tags": ["carcinoma", "cell", "genome", "head", "neck", "squamous", "squamous cell", "squamous cell carcinoma"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-24089_A-AFFY-44", "slug": "expression-data-from-hpv-and-hpv-squamous-cell-car", "geo_gds_id": "", "name": "Expression data from HPV(-) and HPV(+) squamous cell carcinoma cell lines", "created": "Sep.15, 2014", "summary": "Oncogenic human papillomaviruses (HPVs) are associated with nearly all carcinomas of the uterine cervix and have also become an increasingly important factor in the etiology of a subset of oropharyngeal tumors.  HPV-associated head and neck cancers (HNSCCs) have a distinct risk profile and appreciate a prognostic advantage compared to HPV-negative HNSCC. We analyzed the genome-wide expression patterns in two HPV(+) and two HPV(-) squamous cell carcinoma (SCC) cell lines. The Affymetrix Human Genome U133 Plus 2.0 Array platform was used to assess genome-wide expression differences between the HPV(+) and HPV(-) cell lines utilizing the RMA normalization package available for R.  Cell lines analyzed: UM-SCC-4, UM-SCC-47, UM-SCC-74A, and CaSki.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24089", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24089/samples/"}