ArrayExpress Uploaderarrayexpress_sidhumanPTHPTHPTHPTHPTHsalinesalinesalinesalinesaline229304The data present global gene expression profile of whole human bones, implanted in SCID mice (SCID-hu model), then engrafted with the...E-GEOD-24068/profile/8773/arrayexpressuploader110bonecellhormonelineliquidmyelomaparathyroid hormonescidDec.12, 2014Falsegene-expression-from-scid-hu-mice-treated-with-salE-GEOD-24068_A-AFFY-44Gene expression from SCID-hu mice treated with saline (control) or intermittent PTHJul.12, 2014The data present global gene expression profile of whole human bones, implanted in SCID mice (SCID-hu model), then engrafted with the myeloma cell line, Hg, and treated with saline or PTH for 4 weeks. SCID-hu mice were prepared by subcutaneous implantation of human bone in SCID mice. The human myeloma cell line, Hg was injected directly into the implanted bone in SCID-hum mice. Upon establishment of myeloma growth as determined by measurement of circulating human immunoglobulins in SCID-hu mice sera, the mice were treated with saline or intermittent PTH (parathyroid hormone, 80 ug/kg/day) for 4 weeks. At the end of the experiment, the human bones from SCID-hu mice were snap frozen in liquid nitrogen. RNA extracted from these bones was subjected to global gene expression profile using Affymetrix U133-Plus microarray.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24068http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24068/samples/