{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "human", "factors": [{"GSM592240": {"TREATMENT": "PTH"}}, {"GSM592240": {"TREATMENT": "PTH"}}, {"GSM592240": {"TREATMENT": "PTH"}}, {"GSM592240": {"TREATMENT": "PTH"}}, {"GSM592240": {"TREATMENT": "PTH"}}, {"GSM592235": {"TREATMENT": "saline"}}, {"GSM592235": {"TREATMENT": "saline"}}, {"GSM592235": {"TREATMENT": "saline"}}, {"GSM592235": {"TREATMENT": "saline"}}, {"GSM592235": {"TREATMENT": "saline"}}], "id": 2293, "pop_total": 0, "platform": 4, "summary_wrapped": "The data present global gene expression profile of whole human bones, implanted in SCID mice (SCID-hu model), then engrafted with the...", "geo_gse_id": "E-GEOD-24068", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 10, "tags": ["bone", "cell", "hormone", "line", "liquid", "myeloma", "parathyroid hormone", "scid"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "gene-expression-from-scid-hu-mice-treated-with-sal", "geo_id_plat": "E-GEOD-24068_A-AFFY-44", "name": "Gene expression from SCID-hu mice treated with saline (control) or intermittent PTH", "created": "Jul.12, 2014", "summary": "The data present global gene expression profile of whole human bones, implanted in SCID mice (SCID-hu model), then engrafted with the myeloma cell line, Hg, and treated with saline or PTH for 4 weeks. SCID-hu mice were prepared by subcutaneous implantation of human bone in SCID mice. The human myeloma cell line, Hg was injected directly into the implanted bone in SCID-hum mice. Upon establishment of myeloma growth as determined by measurement of circulating human immunoglobulins in SCID-hu mice sera, the mice were treated with saline or intermittent PTH (parathyroid hormone, 80 ug/kg/day) for 4 weeks. At the end of the experiment, the human bones from SCID-hu mice were snap frozen in liquid nitrogen. RNA extracted from these bones was subjected to global gene expression profile using Affymetrix U133-Plus microarray.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24068", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-24068/samples/"}