ArrayExpress Uploader061993wkwild type littermates3wkwild type littermates3wkTransgenic, uroplakin II promoter driving expression of SV40Tag3wkTransgenic, uroplakin II promoter driving expression of SV40Tag6wkwild type littermates6wkTransgenic, uroplakin II promoter driving expression of SV40Tag6wkTransgenic, uroplakin II promoter driving expression of SV40Tag20wkwild type littermates20wkwild type littermates20wkTransgenic, uroplakin II promoter driving expression of SV40Tag20wkTransgenic, uroplakin II promoter driving expression of SV40Tag30wkwild type littermates30wkwild type littermates30wkTransgenic, uroplakin II promoter driving expression of SV40Tag30wkTransgenic, uroplakin II promoter driving expression of SV40Tagarrayexpress_sid6We have identified genes that are differentially expressed between the bladders of UPII-SV40Tag mice and their age-matched wild-type...20501863E-GEOD-23845/profile/8773/arrayexpressuploader215carcinomaurotheliumDec.12, 2014Falsetime-course-for-bladder-ucc-development-in-upii-svE-GEOD-23845_A-AFFY-45Time course for bladder UCC development in UPII-SV40Tag miceNov.11, 2014We have identified genes that are differentially expressed between the bladders of UPII-SV40Tag mice and their age-matched wild-type littermates at 3, 6, 20, and 30 weeks of age. These are ages that correspond to premalignant, carcinoma in situ, and early-stage and later stage invasive UCC, respectively Analysis of the microarray data sets has revealed ∼1,900 unique genes differentially expressed (≥3-fold difference at one or more time points) between wild-type and UPII-SV40Tag urothelium during the time course of tumor development. RNA from the urothelium of duplicate UPII-SV40Tag hemizygous and age-matched wild type littermate mice was isolated at 3, 6, 20, and 30 weeks of age and gene expression profiles were obtained.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-23845mousehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-23845/samples/