ArrayExpress Uploader06173wild typec-Maf KOarrayexpress_sid6Homozygous disruption of c-Maf led to embryonic lethality and impaired erythroblastic island formation. c-Maf is expressed in the fetal...21628412E-GEOD-23305/profile/8773/arrayexpressuploader12celllivermacrophageDec.12, 2014Falsewt-vs-c-maf-ko-fetal-liver-macrophageE-GEOD-23305_A-AFFY-45WT vs c-Maf KO fetal liver macrophageNov.11, 2014Homozygous disruption of c-Maf led to embryonic lethality and impaired erythroblastic island formation. c-Maf is expressed in the fetal liver macrophages. It suggests that macrophages are responsible for the lethality of c-Maf knock-out embryos. To search downstream genes of c-Maf, we surveyed genes associated with macrophage function by microarray analysis. keywords: c-Maf, macrophage, erythroblastic islands, WT (c-Maf WT) and c-Maf KO (c-Maf KO) fetal liver macrophages were sorted by a FACSAria cell sorter. Total RNAs from those macrophages were prepared using RNeasy Kit. Genes down-regulated in c-Maf KO macrophages were searched by GeneSpring software.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-23305mousehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-23305/samples/