{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 6173, "factors": [{"GSM571897": {"GENOTYPE/VARIATION": "wild type"}}, {"GSM571898": {"GENOTYPE/VARIATION": "c-Maf KO"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Homozygous disruption of c-Maf led to embryonic lethality and impaired erythroblastic island formation. c-Maf is expressed in the fetal...", "pubmed_id": 21628412, "geo_gse_id": "E-GEOD-23305", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 2, "tags": ["cell", "liver", "macrophage"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "wt-vs-c-maf-ko-fetal-liver-macrophage", "geo_id_plat": "E-GEOD-23305_A-AFFY-45", "name": "WT vs c-Maf KO fetal liver macrophage", "created": "Nov.11, 2014", "summary": "Homozygous disruption of c-Maf led to embryonic lethality and impaired erythroblastic island formation. c-Maf is expressed in the fetal liver macrophages. It suggests that macrophages are responsible for the lethality of c-Maf knock-out embryos. To search downstream genes of c-Maf, we surveyed genes associated with macrophage function by microarray analysis. keywords: c-Maf, macrophage, erythroblastic islands,  WT (c-Maf WT) and c-Maf KO (c-Maf KO) fetal liver macrophages were sorted by a FACSAria cell sorter. Total RNAs from those macrophages were prepared using RNeasy Kit. Genes down-regulated in c-Maf KO macrophages were searched by GeneSpring software.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-23305", "species": "mouse", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-23305/samples/"}