{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM570750": {"I.P.INJECTION": "saline", "INNOCULATION": "Normal Brain Homogenate (NBH)"}}, {"GSM570750": {"I.P.INJECTION": "saline", "INNOCULATION": "Normal Brain Homogenate (NBH)"}}, {"GSM570750": {"I.P.INJECTION": "saline", "INNOCULATION": "Normal Brain Homogenate (NBH)"}}, {"GSM570753": {"I.P.INJECTION": "500ug/kg LPS", "INNOCULATION": "Normal Brain Homogenate (NBH)"}}, {"GSM570753": {"I.P.INJECTION": "500ug/kg LPS", "INNOCULATION": "Normal Brain Homogenate (NBH)"}}, {"GSM570753": {"I.P.INJECTION": "500ug/kg LPS", "INNOCULATION": "Normal Brain Homogenate (NBH)"}}, {"GSM570756": {"I.P.INJECTION": "saline", "INNOCULATION": "ME7 prion disease"}}, {"GSM570756": {"I.P.INJECTION": "saline", "INNOCULATION": "ME7 prion disease"}}, {"GSM570756": {"I.P.INJECTION": "saline", "INNOCULATION": "ME7 prion disease"}}, {"GSM570759": {"I.P.INJECTION": "500ug/kg LPS", "INNOCULATION": "ME7 prion disease"}}, {"GSM570759": {"I.P.INJECTION": "500ug/kg LPS", "INNOCULATION": "ME7 prion disease"}}, {"GSM570759": {"I.P.INJECTION": "500ug/kg LPS", "INNOCULATION": "ME7 prion disease"}}], "id": 6170, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "To investigate the inflammatory response in neurodegenerative disease during an episode of systemic inflammation using the ME7 prion...", "geo_gse_id": "E-GEOD-23182", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 12, "tags": ["brain", "disease", "hippocampus", "neurodegenerative disease", "volume"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "systemic-inflammation-modulates-fc-receptor-expres", "geo_id_plat": "E-GEOD-23182_A-AFFY-45", "name": "Systemic inflammation modulates Fc receptor expression on microglia in chronic neurodegeneration", "created": "Nov.11, 2014", "summary": "To investigate the inflammatory response in neurodegenerative disease during an episode of systemic inflammation using the ME7 prion model. Comparison of ME7-infected mice with mice innoculated with Normal brain homogenate (NBH). 18 weeks post-innoculation mice were administered 500ug/kg LPS or an equivalent volume of saline as a control. Total RNA was extracted from the hippocampus, amplified and reverse transcribed to cDNA using WT ovation kit and hybridised to mouse 430_2.0 Affymetrix Arrays. There were three biological replicates (individual  mice) per group.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-23182", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-23182/samples/"}