ArrayExpress Uploader0mousePostnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total retinas PicciottoChrnb2-/- (verified by PCR from tail snip, parents are Picciotto mutant)Postnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total retinas PicciottoChrnb2-/- (verified by PCR from tail snip, parents are Picciotto mutant)Postnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total retinas PicciottoChrnb2-/- (verified by PCR from tail snip, parents are Picciotto mutant)Postnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total retinas XuChrnb2-/- (verified by PCR from tail snip, parents are Xu mutant)Postnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total retinas XuChrnb2-/- (verified by PCR from tail snip, parents are Xu mutant)Postnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total retinas XuChrnb2-/- (verified by PCR from tail snip, parents are Xu mutant)Postnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total retinas not specifiedwild typePostnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total retinas not specifiedwild typePostnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total retinas not specifiedwild typePostnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total lateral geniculate nucleus (LGN) PicciottoChrnb2-/- (verified by PCR from tail snip, parents are Picciotto mutant)Postnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total lateral geniculate nucleus (LGN) PicciottoChrnb2-/- (verified by PCR from tail snip, parents are Picciotto mutant)Postnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total lateral geniculate nucleus (LGN) PicciottoChrnb2-/- (verified by PCR from tail snip, parents are Picciotto mutant)Postnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total lateral geniculate nucleus (LGN) XuChrnb2-/- (verified by PCR from tail snip, parents are Xu mutant)Postnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total lateral geniculate nucleus (LGN) XuChrnb2-/- (verified by PCR from tail snip, parents are Xu mutant)Postnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total lateral geniculate nucleus (LGN) XuChrnb2-/- (verified by PCR from tail snip, parents are Xu mutant)Postnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total lateral geniculate nucleus (LGN) not specifiedwild typePostnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total lateral geniculate nucleus (LGN) not specifiedwild typePostnatal day 4 (before retinal ganglion cell segregation in lateral geniculate nucleus)left and right total lateral geniculate nucleus (LGN) not specifiedwild typeAdult (after retinal ganglion cell segregation in lateral geniculate nucleus is complete)left and right total retinas1542PicciottoChrnb2-/- (verified by PCR from tail snip, parents are Picciotto mutant)Adult (after retinal ganglion cell segregation in lateral geniculate nucleus is complete)left and right total retinas1543PicciottoChrnb2-/- (verified by PCR from tail snip, parents are Picciotto mutant)Adult (after retinal ganglion cell segregation in lateral geniculate nucleus is complete)left and right total retinas77XuChrnb2-/- (verified by PCR from tail snip, parents are Xu mutant)Adult (after retinal ganglion cell segregation in lateral geniculate nucleus is complete)left and right total retinas78XuChrnb2-/- (verified by PCR from tail snip, parents are Xu mutant)Adult (after retinal ganglion cell segregation in lateral geniculate nucleus is complete)left and right total retinas748not specifiedwild typeAdult (after retinal ganglion cell segregation in lateral geniculate nucleus is complete)left and right total retinas763not specifiedwild type6140arrayexpress_sid6Mice lacking the beta 2 subunit (Chrnb2) of the neuronal nicotinic acetylcholine receptor display altered retinal waves and disorganized...E-GEOD-22824/profile/8773/arrayexpressuploader524acetylcholineacetylcholine receptorganglionlateralnicotinic acetylcholine receptorretinaDec.12, 2014FalseE-GEOD-22824_A-AFFY-45gene-expression-in-retina-and-lgn-of-wild-type-andGene expression in retina and LGN of wild type and Chrnb2-/- miceNov.11, 2014Mice lacking the beta 2 subunit (Chrnb2) of the neuronal nicotinic acetylcholine receptor display altered retinal waves and disorganized projections of the retinal ganglion cells to the lateral geniculate nucleus (LGN). mRNA populations from retinas and LGN from Chrnb2-/-and wild type (C57BL/6J) mice were compared at 4 days postnatal, when RGC segregation to the LGN begins in WT mice. Retinal mRNAs were also compared at adulthood. Using microarray hybridization, we identified transcripts which are differentially expressed between Chrnb2-/- and wild type animals in these two tissues at these two ages. mRNA was isolated from retina and LGN of three male littermates each of WT and Chrnb2-/- mice at P4. mRNA from retinas of two adult male littermates of each type was also examined.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-22824http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-22824/samples/