ArrayExpress Uploaderarrayexpress_sidhumanlung adenocarcinoma cell line CL1-5control shRNA expressionlung adenocarcinoma cell line CL1-5G9a knockdownlung adenocarcinoma cell line CL1-0control vector expressionlung adenocarcinoma cell line CL1-0G9a overexpression373604G9a is the major mammalian H3-K9 methyltransferase that targets euchromatic regionsand is essential for murine embryogenesis . We...E-GEOD-22810/profile/8773/arrayexpressuploader24adenocarcinomalunglung adenocarcinomaDec.12, 2014FalseE-GEOD-22810_A-AFFY-44expression-data-from-g9a-overexpression-and-knockdExpression data from G9a overexpression and knockdown lung cancer cell linesSep.15, 2014G9a is the major mammalian H3-K9 methyltransferase that targets euchromatic regionsand is essential for murine embryogenesis . We demonstrate that G9a is endowed with methyltransferase activity to concomitantly repress the downstream effector Ep-CAM, thereby promoting the invasion step of the invasion-metastasis cascade. We used microarrays to detail the G9a regulated gene expression underlying invasion-metastasis cascade and identified distinct classes of up-regulated genes during this process. Lung adenocarcinoma cells with G9a knockdown or overexpression were selected for RNA extraction and hybridization on Affymetrix microarrays.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-22810http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-22810/samples/