ArrayExpress Uploader0human3663arrayexpress_sid4Although intestinal microbiota play a pivotal role in the development of host immune system this biological issue was not so far studied...E-GEOD-21930/profile/8773/arrayexpressuploader03immune systempointDec.12, 2014FalseE-GEOD-21930_A-AFFY-44expression-data-from-caco-2-cells-co-cultivated-wiExpression data from Caco-2 cells co-cultivated with B. animalis subsp. lactis BB-12Sep.15, 2014Although intestinal microbiota play a pivotal role in the development of host immune system this biological issue was not so far studied in great detail. In this study we examined immune response of Caco-2 enterocytes after incubation with common probiotic Bifidobacterium animalis subsp. lactis BB-12 for 4 hours. We used microarrays to inspect the global gene expression of Caco-2 cells upon co-culturing with B. animalis subsp. lactis BB-12 and several distinct immune-related genes up-regulated during this process. One time point (T4) and two controls (T0) were analysed. T0 represent differentiated Caco-2 cells cultivated for 3 weeks. T4 represents differentiated Caco-2 cells cultivated for 3 weeks plus consequent 4 hours of co-cultivation with B. animalis subsp. lactis BB-12. 3 technical replicates for T0-1, T0-2 or T4 were pooled to a single sample, RNA extracted and further used in gene expression experiments.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-21930http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-21930/samples/