ArrayExpress Uploaderarrayexpress_sid6060heterozygous for Rosa26-rtTA2 transgenenoneheterozygous for Rosa26-rtTA2 transgenenoneheterozygous for Rosa26-rtTA2 transgeneACE2heterozygous for Rosa26-rtTA2 transgeneACE2heterozygous for Rosa26-rtTA2 and TetO7-Bmpr2-R899X transgenesACE2heterozygous for Rosa26-rtTA2 and TetO7-Bmpr2-R899X transgenesACE2heterozygous for Rosa26-rtTA2 and TetO7-Bmpr2-R899X transgenesnoneheterozygous for Rosa26-rtTA2 and TetO7-Bmpr2-R899X transgenesnone06BMPR2 mutation causes pulmonary arterial hypertension (PAH); ACE2 treatment can resolve established BMPR2-mediated PAH. The purpose of...E-GEOD-21583/profile/8773/arrayexpressuploader28hypertensionDec.12, 2014Falseeffects-of-ace2-on-bmpr2-mutation-mediated-defectsE-GEOD-21583_A-AFFY-45Effects of ACE2 on BMPR2 mutation-mediated defects in gene expressionNov.11, 2014BMPR2 mutation causes pulmonary arterial hypertension (PAH); ACE2 treatment can resolve established BMPR2-mediated PAH. The purpose of this study was to uncover the molecular mechanism behind this. Four groups: +/- ACE2 and +/- BMPR2 transgene, two arrays each, each array a pool of three animals.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-21583mousehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-21583/samples/