{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "id": 6060, "factors": [{"GSM538875": {"GENOTYPE": "heterozygous for Rosa26-rtTA2 transgene", "TREATMENT": "none"}}, {"GSM538875": {"GENOTYPE": "heterozygous for Rosa26-rtTA2 transgene", "TREATMENT": "none"}}, {"GSM538877": {"GENOTYPE": "heterozygous for Rosa26-rtTA2 transgene", "TREATMENT": "ACE2"}}, {"GSM538877": {"GENOTYPE": "heterozygous for Rosa26-rtTA2 transgene", "TREATMENT": "ACE2"}}, {"GSM538879": {"GENOTYPE": "heterozygous for Rosa26-rtTA2 and TetO7-Bmpr2-R899X transgenes", "TREATMENT": "ACE2"}}, {"GSM538879": {"GENOTYPE": "heterozygous for Rosa26-rtTA2 and TetO7-Bmpr2-R899X transgenes", "TREATMENT": "ACE2"}}, {"GSM53888": {"GENOTYPE": "heterozygous for Rosa26-rtTA2 and TetO7-Bmpr2-R899X transgenes", "TREATMENT": "none"}}, {"GSM53888": {"GENOTYPE": "heterozygous for Rosa26-rtTA2 and TetO7-Bmpr2-R899X transgenes", "TREATMENT": "none"}}], "pop_total": 0, "platform": 6, "summary_wrapped": "BMPR2 mutation causes pulmonary arterial hypertension (PAH); ACE2 treatment can resolve established BMPR2-mediated PAH. The purpose of...", "geo_gse_id": "E-GEOD-21583", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 8, "tags": ["hypertension"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "effects-of-ace2-on-bmpr2-mutation-mediated-defects", "geo_id_plat": "E-GEOD-21583_A-AFFY-45", "name": "Effects of ACE2 on BMPR2 mutation-mediated defects in gene expression", "created": "Nov.11, 2014", "summary": "BMPR2 mutation causes pulmonary arterial hypertension (PAH); ACE2 treatment can resolve established BMPR2-mediated PAH. The purpose of this study was to uncover the molecular mechanism behind this. Four groups: +/- ACE2 and +/- BMPR2 transgene, two arrays each, each array a pool of three animals.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-21583", "species": "mouse", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-21583/samples/"}