ArrayExpress Uploader03640sensitiveSCC1sensitiveSCC1sensitiveSCC1resistant1Cc8resistant1Cc8resistant1Cc8arrayexpress_sid4To determine the mechanism of cetuximab-resistance in head and neck cancer, a cetuximab-sensitive cell line (SCC1) and its cetuximab-...20856931E-GEOD-21483/profile/8773/arrayexpressuploader26cancercellheadhead and neck cancerlineneckneck cancerpointDec.12, 2014Falseregulation-of-hb-egf-by-mir-212-and-acquired-cetuxE-GEOD-21483_A-AFFY-44Regulation of HB-EGF by miR-212 and acquired cetuximab-resistance in head and neck cancerSep.15, 2014To determine the mechanism of cetuximab-resistance in head and neck cancer, a cetuximab-sensitive cell line (SCC1) and its cetuximab-resistant derivative (1Cc8) were analyzed for differentially expressed genes using DNA microarrays. 900 differentially expressed genes were found using the statistical cut-off point of one-way ANOVA with FDR less than 1%. The SCC1 and 1Cc8 cell lines were grown in biological triplicates. Total RNA was isolated and array experiments were performed. The supplementary file 'GSE21483_differentially_expressed_genes.txt' includes the list of differentially expressed genes that were identified.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-21483humanhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-21483/samples/