{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 3640, "factors": [{"GSM53704": {"CETUXIMAB SENSITIVITY": "sensitive", "CELL LINE": "SCC1"}}, {"GSM53704": {"CETUXIMAB SENSITIVITY": "sensitive", "CELL LINE": "SCC1"}}, {"GSM53704": {"CETUXIMAB SENSITIVITY": "sensitive", "CELL LINE": "SCC1"}}, {"GSM537044": {"CETUXIMAB SENSITIVITY": "resistant", "CELL LINE": "1Cc8"}}, {"GSM537044": {"CETUXIMAB SENSITIVITY": "resistant", "CELL LINE": "1Cc8"}}, {"GSM537044": {"CETUXIMAB SENSITIVITY": "resistant", "CELL LINE": "1Cc8"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "To determine the mechanism of cetuximab-resistance in head and neck cancer, a cetuximab-sensitive cell line (SCC1) and its cetuximab-...", "pubmed_id": 20856931, "geo_gse_id": "E-GEOD-21483", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 6, "tags": ["cancer", "cell", "head", "head and neck cancer", "line", "neck", "neck cancer", "point"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "regulation-of-hb-egf-by-mir-212-and-acquired-cetux", "geo_id_plat": "E-GEOD-21483_A-AFFY-44", "name": "Regulation of HB-EGF by miR-212 and acquired cetuximab-resistance in head and neck cancer", "created": "Sep.15, 2014", "summary": "To determine the mechanism of cetuximab-resistance in head and neck cancer, a cetuximab-sensitive cell line (SCC1) and its cetuximab-resistant derivative (1Cc8) were analyzed for differentially expressed genes using DNA microarrays. 900 differentially expressed genes were found using the statistical cut-off point of one-way ANOVA with FDR less than 1%. The SCC1 and 1Cc8 cell lines were grown in biological triplicates. Total RNA was isolated and array experiments were performed.  The supplementary file 'GSE21483_differentially_expressed_genes.txt' includes the list of differentially expressed genes that were identified.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-21483", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-21483/samples/"}