ArrayExpress Uploader0humansiLucsiIFITM13613arrayexpress_sid4Interferon-induced transmembrane protein 1 (IFITM1) is one of the three members of the interferon-induced transmembrane family and has...E-GEOD-20923/profile/8773/arrayexpressuploader12adenocarcinomacancercolorectal adenocarcinomacolorectal cancerproteinDec.12, 2014Falseeffects-of-ifitm1-knockdown-in-colorectal-cancerE-GEOD-20923_A-AFFY-44Effects of IFITM1 knockdown in colorectal cancerSep.15, 2014Interferon-induced transmembrane protein 1 (IFITM1) is one of the three members of the interferon-induced transmembrane family and has recently been identified as a new molecular marker in human colorectal cancer. However, its functional roles in colorectal cancer are still elusive. In this study, we investigate the gene expression profiling of HT-29 cells with IFITM1 knockdown. We revealed that several invasive- and carcinogenesis-related genes were differentially expressed. We transfected siRNAs targeting firefly luciferase and human IFITM1 mRNAs into HT-29 colorectal adenocarcinoma cells. At 72 h post-transfection, total RNA was harvested for microarray hybridization. A siLuc-transfected sample was used as the baseline control.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-20923http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-20923/samples/