{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM523459": {"SIRNA": "siLuc"}}, {"GSM523460": {"SIRNA": "siIFITM1"}}], "id": 3613, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Interferon-induced transmembrane protein 1 (IFITM1) is one of the three members of the interferon-induced transmembrane family and has...", "geo_gse_id": "E-GEOD-20923", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 2, "tags": ["adenocarcinoma", "cancer", "colorectal adenocarcinoma", "colorectal cancer", "protein"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "effects-of-ifitm1-knockdown-in-colorectal-cancer", "geo_id_plat": "E-GEOD-20923_A-AFFY-44", "name": "Effects of IFITM1 knockdown in colorectal cancer", "created": "Sep.15, 2014", "summary": "Interferon-induced transmembrane protein 1 (IFITM1) is one of the three members of the interferon-induced transmembrane family and has recently been identified as a new molecular marker in human colorectal cancer. However, its functional roles in colorectal cancer are still elusive. In this study, we investigate the gene expression profiling of HT-29 cells with IFITM1 knockdown. We revealed that several invasive- and carcinogenesis-related genes were differentially expressed. We transfected siRNAs targeting firefly luciferase and human IFITM1 mRNAs into HT-29 colorectal adenocarcinoma cells. At 72 h post-transfection, total RNA was harvested for microarray hybridization. A siLuc-transfected sample was used as the baseline control.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-20923", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-20923/samples/"}