ArrayExpress Uploaderarrayexpress_sidmouseC.albicans Initial Signature Cohorthealthy1C.albicans Initial Signature Cohorthealthy1C.albicans Initial Signature Cohorthealthy1C.albicans Initial Signature Cohorthealthy1C.albicans Initial Signature Cohorthealthy4C.albicans Initial Signature Cohortcandida1C.albicans Initial Signature Cohortcandida1C.albicans Initial Signature Cohortcandida1C.albicans Initial Signature Cohortcandida1C.albicans Initial Signature Cohortcandida1C.albicans Initial Signature Cohortcandida1C.albicans Initial Signature Cohortcandida1C.albicans Initial Signature Cohortcandida1C.albicans Initial Signature Cohortcandida4C.albicans Initial Signature Cohortcandida2C.albicans Initial Signature Cohortcandida2C.albicans Initial Signature Cohortcandida2C.albicans Initial Signature Cohortcandida2C.albicans Initial Signature Cohortcandida2C.albicans Initial Signature Cohortcandida2C.albicans Initial Signature Cohortcandida3C.albicans Initial Signature Cohortcandida3C.albicans Initial Signature Cohortcandida3C.albicans Initial Signature Cohortcandida3C.albicans Initial Signature Cohortcandida3C.albicans Initial Signature Cohortcandida3C.albicans Initial Signature Cohortcandida3C.albicans Initial Signature Cohortcandida4C.albicans Initial Signature Cohortcandida4C.albicans Initial Signature Cohortcandida4C.albicans Initial Signature Cohortcandida4C.albicans Initial Signature Cohortcandida4C.albicans Initial Signature Cohortcandida4C.albicans Initial Signature Cohorthealthy1C.albicans Initial Signature Cohorthealthy1C.albicans Initial Signature Cohorthealthy1C.albicans Initial Signature Cohorthealthy1C.albicans Initial Signature Cohorthealthy4C.albicans Initial Signature Cohorthealthy4C.albicans Initial Signature Cohorthealthy4C.albicans Signature Validation Cohortcandida1C.albicans Signature Validation Cohortcandida1C.albicans Signature Validation Cohortcandida1C.albicans Signature Validation Cohortcandida1C.albicans Signature Validation Cohortcandida1C.albicans Signature Validation Cohortcandida1C.albicans Signature Validation Cohortcandida2C.albicans Signature Validation Cohortcandida2C.albicans Signature Validation Cohortcandida2C.albicans Signature Validation Cohortcandida2C.albicans Signature Validation Cohortcandida2C.albicans Signature Validation Cohortcandida2C.albicans Signature Validation Cohortcandida2C.albicans Signature Validation Cohortcandida2C.albicans Signature Validation Cohortcandida3C.albicans Signature Validation Cohortcandida3C.albicans Signature Validation Cohortcandida3C.albicans Signature Validation Cohortcandida3C.albicans Signature Validation Cohorthealthy1C.albicans Signature Validation Cohorthealthy1S. aureus Exposure Cohortstaph2S. aureus Exposure Cohortstaph1S. aureus Exposure Cohortstaph1S. aureus Exposure Cohortstaph2S. aureus Exposure Cohortstaph2S. aureus Exposure Cohortstaph2S. aureus Exposure Cohortstaph2S. aureus Exposure Cohortstaph3S. aureus Exposure Cohortstaph3S. aureus Exposure Cohorthealthy1S. aureus Exposure Cohorthealthy1S. aureus Exposure Cohorthealthy1846308Focusing on host response to infection, we utilized a murine model to develop a  blood gene expression signature that accurately...E-GEOD-20524/profile/8773/arrayexpressuploader372kidneyrightright kidneyDec.12, 2014Falseblood-gene-expression-signatures-predict-invasiveE-GEOD-20524_A-AFFY-36Blood Gene Expression Signatures Predict Invasive CandidiasisNov.24, 2014Focusing on host response to infection, we utilized a murine model to develop a  blood gene expression signature that accurately classified mice with candidemia and distinguished candidemia from S. aureus bacteremia.  Validation of the signature was achieved in an independent cohort of mice. BALB/c male mice were injected with either normal saline, C.albicans, or S.aureus and sacrificed at pre-set time points of 24, 48, 72-96 hrs (Infection Duration). Blood was placed in RNA Later (R) for RNA expression analysis and the right kidney collected for analysis of pathogen burden.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-20524http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-20524/samples/