{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "human", "factors": [{"GSM506907": {"compound": "none", "dose": "  "}}, {"GSM506908": {"compound": "LMP-420", "dose": "2"}}, {"GSM506907": {"compound": "none", "dose": "  "}}, {"GSM506908": {"compound": "LMP-420", "dose": "2"}}, {"GSM506907": {"compound": "none", "dose": "  "}}, {"GSM506908": {"compound": "LMP-420", "dose": "2"}}, {"GSM506907": {"compound": "none", "dose": "  "}}, {"GSM506908": {"compound": "LMP-420", "dose": "2"}}, {"GSM506907": {"compound": "none", "dose": "  "}}, {"GSM506908": {"compound": "LMP-420", "dose": "2"}}, {"GSM506907": {"compound": "none", "dose": "  "}}, {"GSM506908": {"compound": "LMP-420", "dose": "2"}}, {"GSM506907": {"compound": "none", "dose": "  "}}, {"GSM506908": {"compound": "LMP-420", "dose": "2"}}, {"GSM506907": {"compound": "none", "dose": "  "}}, {"GSM506908": {"compound": "LMP-420", "dose": "2"}}, {"GSM506907": {"compound": "none", "dose": "  "}}, {"GSM506908": {"compound": "LMP-420", "dose": "2"}}, {"GSM506907": {"compound": "none", "dose": "  "}}, {"GSM506908": {"compound": "LMP-420", "dose": "2"}}, {"GSM506907": {"compound": "none", "dose": "  "}}, {"GSM506908": {"compound": "LMP-420", "dose": "2"}}, {"GSM506907": {"compound": "none", "dose": "  "}}, {"GSM506908": {"compound": "LMP-420", "dose": "2"}}, {"GSM506907": {"compound": "none", "dose": "  "}}, {"GSM506908": {"compound": "LMP-420", "dose": "2"}}], "id": 3575, "pop_total": 0, "platform": 4, "summary_wrapped": "[original title] LMP-420: a novel purine nucleoside analogue with potent cytotoxic effects for chronic lymphocytic leukemia cells and...", "pubmed_id": 20613784, "geo_gse_id": "E-GEOD-20211", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 26, "tags": ["chronic lymphocytic leukemia", "leukemia", "purine"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-by-array-of-human-chroni-2", "geo_id_plat": "E-GEOD-20211_A-AFFY-44", "name": "Transcription profiling by array of human chronic lymphocytic leukemia cells after treatment with LMP-420", "created": "Sep.15, 2014", "summary": "[original title] LMP-420: a novel purine nucleoside analogue with potent cytotoxic effects for chronic lymphocytic leukemia cells and minimal toxicity for normal hematopoietic cells.  LMP-420 induces cytotoxicity and apoptosis to CLL cells in vitro without any negative effects to normal immune cells. This gene expression experiment compares CLL cells treated with LMP-420 versus media alone to investigate the mechanism of action of LMP-420. CLL cells from 13 patients were treated with LMP-420 or media for 24 hours, then RNA was extracted and assayed on U133Plus2 GeneChips.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-20211", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-20211/samples/"}