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Home › Dataset Library › Comparison of Fusobacterium Nucleatum stimulated and unstimulated neutrophils

Dataset: Comparison of Fusobacterium Nucleatum stimulated and unstimulated neutrophils

Neutrophils are known to be stimulated by different periodontal bacteria to produce reactive oxygen species and cytokines. It is...

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Neutrophils are known to be stimulated by different periodontal bacteria to produce reactive oxygen species and cytokines. It is inportant to investigate the gene changes made by bacteria of importance, of which, for periodontal disease, fusobaterium nucleatum is one. we used microarrays to investigate gene experssion changes in peripheral blood neutrophils werwhich e stimulated with or with out Fusobacterium Nucleatum (10953). Neutrophils from periodonatlly healthy individuals (n=4) were isolated and stimulated for 3hrs with or without fusobaterium nucleatum (10953). RNA was then extracted from these and pooled before hybridization on Affymetrix microarrays

Species:
human

Samples:
4

Source:
E-GEOD-20151

PubMed:
20663022

Updated:
Dec.12, 2014

Registered:
Jun.19, 2014


Factors: (via ArrayExpress)
Sample CELL TYPE
GSM505622 stimulated neutrophil
GSM505622 stimulated neutrophil
GSM313632 unstimulated neutrophil
GSM313632 unstimulated neutrophil

Tags

  • disease
  • periodontal disease
  • peripheral

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