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Home › Dataset Library › Expression data from hyperplastic polyps and normal colonic mucosa from patients with familial and sporadic HPPS

Dataset: Expression data from hyperplastic polyps and normal colonic mucosa from patients with familial and sporadic HPPS

Expression data from hyperplastic polyps and normal colonic mucosa from patients with familial and sporadic hyperplastic polyposis...

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Expression data from hyperplastic polyps and normal colonic mucosa from patients with familial and sporadic hyperplastic polyposis syndrome (HPPS). We aim to characterize at a molecular level a cohort of hyperplastic lesions from HPPS patients with and without family history. RNA from hyperplastic polyps and normal colonic mucosa (proximal and distal) from patients with familial and sporadic HPPS were included in this study. Total RNA was isolated from each tissue sample, quantified and its quality evaluated. cRNA preparation, hybridization and analysis of results was performed according to Affymetrix recommendations. cRNA was hybridised in the GeneChip array (Human Genome U133 Plus 2.0, Affymetrix), and the intensity was measured.

Species:
human

Samples:
9

Source:
E-GEOD-19963

Updated:
Dec.12, 2014

Registered:
Sep.15, 2014


Factors: (via ArrayExpress)
Sample COLON LOCATION HEREDITARY NATURE OF HPPS HISTOLOGY
GSM498702 not available familial hyperplastic polyp
GSM498703 distal familial hyperplastic polyp
GSM498704 distal sporadic hyperplastic polyp
GSM498705 proximal sporadic hyperplastic polyp
GSM498705 proximal sporadic hyperplastic polyp
GSM498707 proximal familial normal colonic mucosa
GSM498708 distal familial normal colonic mucosa
GSM498707 proximal familial normal colonic mucosa
GSM498708 distal familial normal colonic mucosa

Tags

  • distal
  • genome
  • mucosa
  • proximal
  • syndrome

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