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Home › Dataset Library › Control of LPS induced gene expression in bone marrow derived macrophages by the p50/p105 subunit of NF-kB and IL-10

Dataset: Control of LPS induced gene expression in bone marrow derived macrophages by the p50/p105 subunit of NF-kB and IL-10

Bone marrow-derived macrophages were produced from mice lacking IL-10 alone (IL10-def) or mice lacking both IL-10 and the p50/p105...

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Bone marrow-derived macrophages were produced from mice lacking IL-10 alone (IL10-def) or mice lacking both IL-10 and the p50/p105 subunit of NF-kB (p50/IL10), and left unstimulated, stimulated with LPS (1 ng/ml) or stimulated with LPS and IL-10 (0.3 ng/ml). There are 12 total samples, with 2 each from the groups described in the summary. Pairwise comparisons between groups were evaluated.

Species:
mouse

Samples:
12

Source:
E-GEOD-19941

Updated:
Dec.12, 2014

Registered:
Nov.24, 2014


Factors: (via ArrayExpress)
Sample STIMULUS GENOTYPE
GSM498282 none IL10-/-
GSM498282 none IL10-/-
GSM498284 none p50-/-IL-10-/-
GSM498284 none p50-/-IL-10-/-
GSM498286 LPS (1ng/ml) IL10-/-
GSM498286 LPS (1ng/ml) IL10-/-
GSM498288 LPS (1ng/ml) p50-/-IL-10-/-
GSM498288 LPS (1ng/ml) p50-/-IL-10-/-
GSM498290 LPS (1ng/ml) + IL10 (0.3 ng/ml) IL10-/-
GSM498290 LPS (1ng/ml) + IL10 (0.3 ng/ml) IL10-/-
GSM498292 LPS (1ng/ml) + IL10 (0.3 ng/ml) p50-/-IL-10-/-
GSM498292 LPS (1ng/ml) + IL10 (0.3 ng/ml) p50-/-IL-10-/-

Tags

  • bone
  • bone marrow
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