ArrayExpress Uploader08457Runx1Runx1Runx1Runx1Runx1Runx1arrayexpress_sid8The HSA21-mES Cell Bank includes, in triplicate clones, thirty-two murine orthologs of HSA21 genes, which can be overexpressed in an...20569505E-GEOD-19836/profile/8773/arrayexpressuploader16cellDec.12, 2014Falsea-mouse-embryonic-stem-cell-bank-for-inducible-oveE-GEOD-19836_A-AFFY-36A mouse Embryonic Stem Cell Bank for inducible overexpression of human chromosome 21 genesNov.24, 2014The HSA21-mES Cell Bank includes, in triplicate clones, thirty-two murine orthologs of HSA21 genes, which can be overexpressed in an inducible manner using the Tet-off system integrated in the Rosa26 locus. The following subset of twenty clones were characterized by microarray analysis: Bach1, Erg, Ets2, Gabpa, ZFP295, Nrip1, Olig1, Olig2, Pknox1, 1810007M14Rik, Runx1, Aire, Sim2, Dscr1, DYRK1A, SNF1LK, Ripk4 , Hunk, Pdxk, Pfkl. Each triplicate clone was transcriptionally profiled by microarray analysis using Affymetrix Mouse 430_2 arrays before and after induction (Affymetrix 430A_2 in case of Runx1), yielding six arrays for each overexpression experiment.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19836mousehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19836/samples/