ArrayExpress Uploaderarrayexpress_sidhumancontrolcontrolcontrolsi221si221si221si222si222si222354404Full title: Expression data from antisense miRNA-221/222 (si221/222) and control inhibitor (GFP) treated fulvestrant-resistant breast...E-GEOD-19777/profile/8773/arrayexpressuploader19breastbreast cancercancercelllineDec.12, 2014FalseE-GEOD-19777_A-AFFY-44antisense-mirna-221222-si221222-and-control-inhibiAntisense miRNA-221/222 (si221/222) and control inhibitor (GFP) treated fulvestrant-resistant breast cancer cellsSep.15, 2014Full title: Expression data from antisense miRNA-221/222 (si221/222) and control inhibitor (GFP) treated fulvestrant-resistant breast cancer cells The expression of miR-221/222 were found to be upregulated in fulvestrant resistant breast cancer cells MCF7-FR compared to its drug-sensitive counterpart MCF7. To investigate the role of miR-221/222 in acquired resistance to fulvestrant, we lowered the level of miR-221/222 in MCF7-FR cells using miRNA inhibitors (antagomirs), and compared gene expression profiles before and after treatment. Fulvestrant-resistant breast cancer cells MCF7-FR (originated from drug-sentitive breast cancer model cell line MCF7) were transient-transfected by antigomirs targeting miR221 or miR222 (i.e. si221, si222). All three cell lines, MCF7-FR, siR221, siRNA222 were subjected to gene expression profiling.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19777http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19777/samples/