{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM491345": {"GENOME/VARIATION": "without DACH1 expression"}}, {"GSM491346": {"GENOME/VARIATION": "with DACH1 expression"}}, {"GSM491345": {"GENOME/VARIATION": "without DACH1 expression"}}, {"GSM491346": {"GENOME/VARIATION": "with DACH1 expression"}}], "id": 3537, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Loss or reduction in function of tumor suppressor genes contributes to tumorigenesis. We identified a novel homozygous deletion of DACH1...", "geo_gse_id": "E-GEOD-19678", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 4, "tags": ["cell", "glioma", "line", "serum"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "dach1-expression-in-u87-cells", "geo_id_plat": "E-GEOD-19678_A-AFFY-44", "name": "DACH1 expression in U87 cells", "created": "Sep.15, 2014", "summary": "Loss or reduction in function of tumor suppressor genes contributes to tumorigenesis. We identified a novel homozygous deletion of DACH1 in gliomas. We generated U87TR-Da glioma cell line, where DACH1 expression could be activated by exposure of cells to doxycycline, and examined changing global gene expression by DACH1 expression. Expression of DACH1 in U87TR-Da cells can be induced by exposure of the cells to doxycycline. We analyzed gene expression profiles of DACH1-induced/repressed U87TR-Da cells. And we also compared gene expression profiles of DACH1-induced/repressed U87TR-Da cells under different culture condition, DMEMF(serum-containing) and NBE(serum-free)", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19678", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19678/samples/"}