ArrayExpress Uploader03531untreateduntreated17AAG17AAGAUY922AUY922CDK-887CDK-887doxorubicindoxorubicinE973E973SN38SN38arrayexpress_sid4The effects of several compounds on the MCF7 human adenocarcinoma mammary cell line were analysed by gene expression profiling. Tested...20679242E-GEOD-19638/profile/8773/arrayexpressuploader114adenocarcinomacelllineDec.12, 2014Falsecompounds-profiling-on-mcf7E-GEOD-19638_A-AFFY-44Compounds profiling on MCF7Sep.15, 2014The effects of several compounds on the MCF7 human adenocarcinoma mammary cell line were analysed by gene expression profiling. Tested compounds: HSP90 inhibitors: 17AAG (Tanespimycin), NVP-AUY922, NMS-E973 (cpd developed at NMS). CDK inhibitors: CDK-887 (cpd developed at NMS). Topoisomerase inhibitors: Doxorubicin, SN38 (active metabolite of Irinotecan). The MCF7 cell line was treated with the different compounds for 6 hours at a dose equal to 5 times the IC50. Untreated MCF7 cells were used as a control. Two replicates per treatment.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19638humanhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19638/samples/