{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 3531, "factors": [{"GSM490029": {"TREATMENT": "untreated"}}, {"GSM490029": {"TREATMENT": "untreated"}}, {"GSM49003": {"TREATMENT": "17AAG"}}, {"GSM49003": {"TREATMENT": "17AAG"}}, {"GSM490033": {"TREATMENT": "AUY922"}}, {"GSM490033": {"TREATMENT": "AUY922"}}, {"GSM490035": {"TREATMENT": "CDK-887"}}, {"GSM490035": {"TREATMENT": "CDK-887"}}, {"GSM490037": {"TREATMENT": "doxorubicin"}}, {"GSM490037": {"TREATMENT": "doxorubicin"}}, {"GSM490039": {"TREATMENT": "E973"}}, {"GSM490039": {"TREATMENT": "E973"}}, {"GSM49004": {"TREATMENT": "SN38"}}, {"GSM49004": {"TREATMENT": "SN38"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "The effects of several compounds on the MCF7 human adenocarcinoma mammary cell line were analysed by gene expression profiling. Tested...", "pubmed_id": 20679242, "geo_gse_id": "E-GEOD-19638", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 14, "tags": ["adenocarcinoma", "cell", "line"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "compounds-profiling-on-mcf7", "geo_id_plat": "E-GEOD-19638_A-AFFY-44", "name": "Compounds profiling on MCF7", "created": "Sep.15, 2014", "summary": "The effects of several compounds on the MCF7 human adenocarcinoma mammary cell line were analysed by gene expression profiling. Tested compounds: HSP90 inhibitors: 17AAG (Tanespimycin), NVP-AUY922,  NMS-E973 (cpd developed at NMS). CDK inhibitors: CDK-887 (cpd developed at NMS). Topoisomerase inhibitors: Doxorubicin, SN38 (active metabolite of Irinotecan).  The MCF7 cell line was treated with the different compounds for 6 hours at a dose equal to 5 times the IC50. Untreated MCF7 cells were used as a control. Two replicates per treatment.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19638", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19638/samples/"}