ArrayExpress Uploader0humansteady stateandrogen deprivationandrogen deprivationandrogen deprivation + Etoposideandrogen deprivation + Merbaronecontrol transfection and androgen deprivationcontrol transfection and androgen deprivationTOPO2B knockdown and androgen deprivationTOPO2B knockdown and androgen deprivation3520arrayexpress_sid4Microarray experiments were carried out to ascertain whether TOP2β is required for DHT induced androgen receptor target gene expression....20601956E-GEOD-19445/profile/8773/arrayexpressuploader19androgencancerprostateprostate cancerserumDec.12, 2014Falselncap-cells-in-response-to-dht-stimulation-and-inhE-GEOD-19445_A-AFFY-44LNCaP cells in response to DHT stimulation and inhibition/knockdown of TOPO2BSep.15, 2014Microarray experiments were carried out to ascertain whether TOP2β is required for DHT induced androgen receptor target gene expression. We investigated the effect of pharmacological inhibition or RNA interference-mediated depletion of TOP2β on gene expression in androgen-dependent LNCaP prostate cancer cells. Analysis of gene expression in LNCaP cells under various conditions including serum starvation, DHT treatment, and DHT treatment combined with TOPO2B pharmacological inhibitors (Merbarone and Etoposide) and TOPO2B-shRNA knockdown.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19445http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19445/samples/