ArrayExpress Uploader0mouseC57Bl/6wildtypeC57Bl/6wildtypeAhRtm1BraAhR knockoutAhRtm1BraAhR knockout8452arrayexpress_sid8[original Title] Comparison of expression data of primary murine melanocytes from aryl hydrocarbon deficient mice and corresponding wild-...E-GEOD-19411/profile/8773/arrayexpressuploader24melaninskinDec.12, 2014Falseexpression-data-of-primary-melanocytes-from-aryl-hE-GEOD-19411_A-AFFY-36Expression data of primary melanocytes from aryl hydrocarbon deficient mice and corresponding wild-type C57BL/6 miceNov.24, 2014[original Title] Comparison of expression data of primary murine melanocytes from aryl hydrocarbon deficient mice and corresponding wild-type C57BL/6 mice Melanin is produced exclusively by melanocytes and melanogenesis is the vital response to protect skin cells against Ultraviolet B (UVB)-induced DNA damage. The aryl hydrocarbon receptor (AhR) is a transcription factor, which may be involved in the physiological tanning response. Normal murine melanocytes express functional AhR. We tested gene expression in WT versus AhR-deficient mice primary murine melanocytes, isolated from the skin and cultivated for several passages. Skin epidermal cells from 2 individual C57BL/6 mice and 2 individual AhR-deficient mice (deletion of exon2, AhRtm1Bra) were grown for 6-8 weeks in selection medium to propagate melanocytes.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19411http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19411/samples/