{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM48277": {"STRAIN": "C57Bl/6", "GENOTYPE/VARIATION": "wildtype"}}, {"GSM48277": {"STRAIN": "C57Bl/6", "GENOTYPE/VARIATION": "wildtype"}}, {"GSM482773": {"STRAIN": "AhRtm1Bra", "GENOTYPE/VARIATION": "AhR knockout"}}, {"GSM482773": {"STRAIN": "AhRtm1Bra", "GENOTYPE/VARIATION": "AhR knockout"}}], "id": 8452, "ownerprofile_id": "arrayexpress_sid", "platform": 8, "summary_wrapped": "[original Title] Comparison of expression data of primary murine melanocytes from aryl hydrocarbon deficient mice and corresponding wild-...", "geo_gse_id": "E-GEOD-19411", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 4, "tags": ["melanin", "skin"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-of-primary-melanocytes-from-aryl-h", "geo_id_plat": "E-GEOD-19411_A-AFFY-36", "name": "Expression data of primary melanocytes from aryl hydrocarbon deficient mice and corresponding wild-type C57BL/6 mice", "created": "Nov.24, 2014", "summary": "[original Title] Comparison of expression data of primary murine melanocytes from aryl hydrocarbon deficient mice and corresponding wild-type C57BL/6 mice  Melanin is produced exclusively by melanocytes and melanogenesis is the vital response to protect skin cells against Ultraviolet B (UVB)-induced DNA damage. The aryl hydrocarbon receptor (AhR) is a transcription factor, which may be involved in the physiological tanning response. Normal murine melanocytes express functional AhR. We tested gene expression in WT versus AhR-deficient mice primary murine melanocytes, isolated from the skin and cultivated for several passages. Skin epidermal cells from 2 individual C57BL/6 mice and 2 individual AhR-deficient mice (deletion of exon2, AhRtm1Bra)  were grown for 6-8 weeks in selection medium to propagate melanocytes.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19411", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19411/samples/"}