{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSE19374GSM480877": {}}, {"GSE19374GSM480878": {}}, {"GSE19374GSM480874": {}}, {"GSE19374GSM480875": {}}, {"GSE19374GSM480876": {}}], "id": 5922, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Macrophages phagocytose bacteria. Certain pathogenic bacteria access and replicate within the cytosol of infected macrophages and induce...", "geo_gse_id": "E-GEOD-19374", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 5, "tags": ["bone", "bone marrow", "cell", "macrophage"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-of-mouse-bone-marrow-der-5", "geo_id_plat": "E-GEOD-19374_A-AFFY-45", "name": "Transcription profiling of mouse bone marrow derived macrophages", "created": "Nov.11, 2014", "summary": "Macrophages phagocytose bacteria. Certain pathogenic bacteria access and replicate within the cytosol of infected macrophages and induce changes in macrophage gene expression by triggering of innate immune receptors and/or the effects of bacterial virulence factors. We used microarray analysis to identify changes in macrophage gene expression following infection with Listeria monocytogenes. Experiment Overall Design: Macrophages were cultured from bone marrow of female C57BL/6 mice using 10% L-cell conditioned media and mock infected (3 chips) or infected with log phase L. monocytogenes (2 chips). Samples were harvested for RNA isolation at 10 h after infection. Experiment Overall Design: Supplementary file below reports Genesifter-processed data: mean (\"P\" only) signal intensities and SEM for the MOCK and LM_INF groups.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19374", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19374/samples/"}