ArrayExpress Uploaderarrayexpress_sidhumansarc_high_lung_fx1Msarcoidosis31Asianhp1MHypersensitivity Pnemonitis42Whitehealth1FHealthy39Latinosarc_low_lung_fx1Fsarcoidosis66Whitehealth1FHealthy66Latinohealth1FHealthy43Whitehealth1MHealthy48Blacksarc_low_lung_fx1Fsarcoidosis53Whitehealth1FHealthy34Blacksarc_high_lung_fx1Fsarcoidosis63Latinosarc_low_lung_fx1Fsarcoidosis57Whitehealth1FHealthy55Whitehp1MHypersensitivity Pnemonitis54Whitehp1FHypersensitivity Pnemonitis66Whitesarc_low_lung_fx1Msarcoidosis43Whitesarc_high_lung_fx1Fsarcoidosis46Whitesarc_low_lung_fx1Msarcoidosis66Whitesarc_low_lung_fx1Fsarcoidosis31Blacksarc_high_lung_fx1Fsarcoidosis37Whitehealth1FHealthy61Whitehealth1FHealthy56Whitehp1FHypersensitivity Pnemonitis50Whitehealth1MHealthy45Whitehealth1MHealthy59Whitehealth2FHealthy34Whitesarc_low_lung_fx2Msarcoidosis60Whitesarc_high_lung_fx2Fsarcoidosis47Whitesarc_low_lung_fx2Msarcoidosis32Whitesarc_high_lung_fx2Fsarcoidosis73Whitesarc_low_lung_fx2Msarcoidosis63Whitehealth2FHealthy53Whitehealth2MHealthy55Whitesarc_low_lung_fx2Fsarcoidosis37Whitehp2MHypersensitivity Pnemonitis63Whitesarc_low_lung_fx2Msarcoidosis35Blacksarc_high_lung_fx2Fsarcoidosis62Whitesarc_high_lung_fx2Fsarcoidosis53Whitehealth2FHealthy70Whitehp2FHypersensitivity Pnemonitis49Latinosarc_low_lung_fx2Msarcoidosis40Whitesarc_low_lung_fx2Fsarcoidosis41Whitehealth2MHealthy42Whitesarc_high_lung_fx2Msarcoidosis44Whitesarc_low_lung_fx2Msarcoidosis56Whitesarc_low_lung_fx2Msarcoidosis40Asiansarc_high_lung_fx2Fsarcoidosis56Whitesarc_high_lung_fx3Fsarcoidosis57Whitesarc_high_lung_fx3Fsarcoidosis53Whitesarc_high_lung_fx3Fsarcoidosis60Whitehealth3FHealthy55Whitehealth3FHealthy43Whitesarc_high_lung_fx3Fsarcoidosis47Blacksarc_low_lung_fx3Fsarcoidosis53Whitehealth3FHealthy60Whitesarc_high_lung_fx3Msarcoidosis51Whitesarc_low_lung_fx3Msarcoidosis54Whitesarc_high_lung_fx3Fsarcoidosis35Whitesarc_low_lung_fx3Msarcoidosis67Whitehealth3FHealthy57Whitehealth3FHealthy62Whitesarc_low_lung_fx3Fsarcoidosis58Whitesarc-vs-bo3Fsarcoid vs. BO40Latinosarc_high_lung_fx3Msarcoidosis63Whitesarc_low_lung_fx3Msarcoidosis51Whitesarc_high_lung_fx3Msarcoidosis50Blacksarc-hcv3FHCV/sarcoid44Black350804We hypothesized that microarray analyses of whole blood gene expression would identify patterns of gene expression useful in the...E-GEOD-19314/profile/8773/arrayexpressuploader666genomehypersensitivityhypersensitivity pneumonitissarcoidosisDec.12, 2014Falsesarcoidosis-specific-markers-from-whole-blood-geneE-GEOD-19314_A-AFFY-44Sarcoidosis-specific markers from whole blood gene expressionSep.15, 2014We hypothesized that microarray analyses of whole blood gene expression would identify patterns of gene expression useful in the diagnosis for sacroidosis and identify inflammatory mediators relevant to the underlying pathophysiology. We analyzed whole blood RNA from 37 patients with sarcoidosis, 20 healthy controls and 6 patients with hypersensitivity pneumonitis using genome-wide expression microarrays. We developed a classification algorithm using a derivation and validation subset approach, analyzed the most discriminative gene expression changes, and confirmed selected expression changes using flow-cytometry.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19314http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-19314/samples/