Dataset: Transcription profiling by array of human umbilical vein endothelial cells with RNAi-mediated knock-down of Egr-3 after treatment with vascular endothelial growth factor
Analysis of umbilical vein endothelial cells (HUVEC) treated with Egr-3 siRNA under the VEGF treatment for 0,1, and 4 h. Egr-3, a member...
Analysis of umbilical vein endothelial cells (HUVEC) treated with Egr-3 siRNA under the VEGF treatment for 0,1, and 4 h. Egr-3, a member of early growth response family, is immediately and dramatically induced by VEGF in HUVEC, which regulates expression of many genes related to endothelial activation. Experiment Overall Design: Total 21 samples were derived from triplicate arrays of VEGF-treated si-Control-transfected cells and duplicate arrays of each of the VEGF-treated si-Egr-3-transfected cells.
- Species:
- human
- Samples:
- 21
- Source:
- E-GEOD-18913
- PubMed:
- 19965691
- Updated:
- Dec.12, 2014
- Registered:
- Sep.15, 2014
Factors:
(via ArrayExpress)
| Sample | time | genotype | compound |
|---|---|---|---|
| GSM468603 | 0 | wild type | none |
| GSM468603 | 0 | wild type | none |
| GSM468605 | 0 | Egr-3 siRNA #1 | none |
| GSM468606 | 0 | Egr-3 siRNA #2 | none |
| GSM468605 | 0 | Egr-3 siRNA #1 | none |
| GSM468606 | 0 | Egr-3 siRNA #2 | none |
| GSM468609 | 1 | wild type | vascular endothelial growth factor |
| GSM468609 | 1 | wild type | vascular endothelial growth factor |
| GSM468609 | 1 | wild type | vascular endothelial growth factor |
| GSM468612 | 1 | Egr-3 siRNA #1 | vascular endothelial growth factor |
| GSM468613 | 1 | Egr-3 siRNA #2 | vascular endothelial growth factor |
| GSM468613 | 1 | Egr-3 siRNA #2 | vascular endothelial growth factor |
| GSM468615 | 4 | wild type | vascular endothelial growth factor |
| GSM468615 | 4 | wild type | vascular endothelial growth factor |
| GSM468617 | 4 | Egr-3 siRNA #1 | vascular endothelial growth factor |
| GSM468617 | 4 | Egr-3 siRNA #1 | vascular endothelial growth factor |
| GSM468619 | 4 | Egr-3 siRNA #2 | vascular endothelial growth factor |
| GSM468619 | 4 | Egr-3 siRNA #2 | vascular endothelial growth factor |
| GSM468603 | 0 | wild type | none |
| GSM468609 | 1 | wild type | vascular endothelial growth factor |
| GSM468615 | 4 | wild type | vascular endothelial growth factor |