ArrayExpress Uploader03482arrayexpress_sid4B19V NS1 is known to be cytotoxic and involved in the pathogenesis of B19V infection. Our previous data demonstrated that NS1 impaired...20890043E-GEOD-18906/profile/8773/arrayexpressuploader018cellDec.12, 2014Falsetranscriptional-profiling-of-b19-virus-nonstructurE-GEOD-18906_A-AFFY-44Transcriptional Profiling of B19 Virus Nonstructure Protein (NS1) transduced CD36+ Erythoid Progenitor Cells (EPCs)Sep.15, 2014B19V NS1 is known to be cytotoxic and involved in the pathogenesis of B19V infection. Our previous data demonstrated that NS1 impaired the cell-cycle progression of the CD36+ EPCs by inducing a stable G2 arrest. Microarray analysis was used to identify genes whose expressions were associated with the NS1-induced G2 arrest. A total of 1045 genes displayed a more than 1.5-fold differential expression in the NS1-transduced cells. Out of 1045 differentially expressed genes, 177 were involved in cell-cycle regulation and 51 were involved in the regulation of cell differentiation. Keywords: RNA CD36+ EPCs were generated from CD34+ stem cells, and transduced with B19V NS1 or control-lentivirus for 12, 24,and 48 hours. Each sample has triplicates. There are 18 samples analyzed.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-18906humanhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-18906/samples/