ArrayExpress Uploader0347216 weeksfetal RPE16 weeksfetal RPE17 weeksfetal RPE17 weeksfetal RPE17 weeksfetal RPE16 weeksfetal RPE16 weeksfetal RPE18 weeksfetal RPE18 weeksfetal RPE16 weeksfetal RPEnot specifiedadult native RPE from 76 y.o. donornot specifiedadult choroid from 76 y.o. donornot specifiedadult native RPE from 78 y.o. donornot specifiedadult native RPE from 89 y.o. donornot specifiednot specifiednot specifiednot specifiednot specifiednot specifiednot specifiednot specifiednot specifiednot specifiednot specifiednot specified16 weeksfetal RPEnot specifiednot specifiednot specifiednot specified16 weeksnative fetal RPE17 weeksnative fetal RPE17 weeksnative fetal RPEnot specifiedadult native RPE from 78 y.o. donor16 weeksfetal RPE16 weeksfetal RPE16 weeksfetal RPE16 weeksfetal RPEarrayexpress_sid4[u'The retinal pigment epithelium (RPE) is a polarized cell layer that is critical for photoreceptor function and survival. It\u2019s...20360305E-GEOD-18811/profile/8773/arrayexpressuploader231cellphotoreceptorDec.12, 2014Falsetranscriptome-analysis-and-molecular-signature-ofE-GEOD-18811_A-AFFY-44Transcriptome Analysis and Molecular Signature of Human Retinal Pigment EpitheliumSep.15, 2014[u'The retinal pigment epithelium (RPE) is a polarized cell layer that is critical for photoreceptor function and survival. It\u2019s unique relationship to the photoreceptors and its specific physiology makes the RPE a critical determinant of human vision. Therefore we performed global expression profiling of native and cultured human fetal and adult RPE and determined a unique set of highly-expressed genes (called the \u201csignature\u201d set) by comparing the observed RPE gene profiles to the Novartis expression database (SymAtlas: ', {u'a': {u'href': u'http://wombat.gnf.org/index.html', u'target': u'_blank', u'$': u'http://wombat.gnf.org/index.html'}}, u') of 78 tissues. A comparative analysis of transcriptomes from human fetal and adult RPE, primary cultures and commonly-used cell lines was performed. Using selection criteria of at least 10-fold higher expression in each of three RPE preparations, we identified 154 RPE signature genes, which were validated by qRT-PCR analysis in RPE and in an independent set of 11 tissues.']http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-18811humanhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-18811/samples/