{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 3472, "factors": [{"GSM466520": {"GESTATIONAL AGE": "16 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466520": {"GESTATIONAL AGE": "16 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466522": {"GESTATIONAL AGE": "17 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466522": {"GESTATIONAL AGE": "17 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466522": {"GESTATIONAL AGE": "17 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466520": {"GESTATIONAL AGE": "16 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466520": {"GESTATIONAL AGE": "16 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466527": {"GESTATIONAL AGE": "18 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466527": {"GESTATIONAL AGE": "18 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466520": {"GESTATIONAL AGE": "16 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466530": {"GESTATIONAL AGE": "not specified", "CELL TYPE": "adult native RPE from 76 y.o. donor"}}, {"GSM46653": {"GESTATIONAL AGE": "not specified", "CELL TYPE": "adult choroid from 76 y.o. donor"}}, {"GSM466532": {"GESTATIONAL AGE": "not specified", "CELL TYPE": "adult native RPE from 78 y.o. donor"}}, {"GSM466533": {"GESTATIONAL AGE": "not specified", "CELL TYPE": "adult native RPE from 89 y.o. donor"}}, {"GSM466534": {"GESTATIONAL AGE": "not specified", "CELL TYPE": "not specified"}}, {"GSM466534": {"GESTATIONAL AGE": "not specified", "CELL TYPE": "not specified"}}, {"GSM466534": {"GESTATIONAL AGE": "not specified", "CELL TYPE": "not specified"}}, {"GSM466534": {"GESTATIONAL AGE": "not specified", "CELL TYPE": "not specified"}}, {"GSM466534": {"GESTATIONAL AGE": "not specified", "CELL TYPE": "not specified"}}, {"GSM466534": {"GESTATIONAL AGE": "not specified", "CELL TYPE": "not specified"}}, {"GSM466520": {"GESTATIONAL AGE": "16 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466534": {"GESTATIONAL AGE": "not specified", "CELL TYPE": "not specified"}}, {"GSM466534": {"GESTATIONAL AGE": "not specified", "CELL TYPE": "not specified"}}, {"GSM466543": {"GESTATIONAL AGE": "16 weeks", "CELL TYPE": "native fetal RPE"}}, {"GSM466544": {"GESTATIONAL AGE": "17 weeks", "CELL TYPE": "native fetal RPE"}}, {"GSM466544": {"GESTATIONAL AGE": "17 weeks", "CELL TYPE": "native fetal RPE"}}, {"GSM466532": {"GESTATIONAL AGE": "not specified", "CELL TYPE": "adult native RPE from 78 y.o. donor"}}, {"GSM466520": {"GESTATIONAL AGE": "16 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466520": {"GESTATIONAL AGE": "16 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466520": {"GESTATIONAL AGE": "16 weeks", "CELL TYPE": "fetal RPE"}}, {"GSM466520": {"GESTATIONAL AGE": "16 weeks", "CELL TYPE": "fetal RPE"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "[u'The retinal pigment epithelium (RPE) is a polarized cell layer that is critical for photoreceptor function and survival. It\\u2019s...", "pubmed_id": 20360305, "geo_gse_id": "E-GEOD-18811", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 31, "tags": ["cell", "photoreceptor"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcriptome-analysis-and-molecular-signature-of", "geo_id_plat": "E-GEOD-18811_A-AFFY-44", "name": "Transcriptome Analysis and Molecular Signature of Human Retinal Pigment Epithelium", "created": "Sep.15, 2014", "summary": "[u'The retinal pigment epithelium (RPE) is a polarized cell layer that is critical for photoreceptor function and survival. It\\u2019s unique relationship to the photoreceptors and its specific physiology makes the RPE a critical determinant of human vision.  Therefore we performed global expression profiling of native and cultured human fetal and adult RPE and determined a unique set of highly-expressed genes (called the \\u201csignature\\u201d set) by comparing the observed RPE gene profiles to the Novartis expression database (SymAtlas: ', {u'a': {u'href': u'http://wombat.gnf.org/index.html', u'target': u'_blank', u'$': u'http://wombat.gnf.org/index.html'}}, u') of 78 tissues. A comparative analysis of transcriptomes from human fetal and adult RPE, primary cultures and commonly-used cell lines was performed. Using selection criteria of at least 10-fold higher expression in each of three RPE preparations, we identified 154 RPE signature genes, which were validated by qRT-PCR analysis in RPE and in an independent set of 11 tissues.']", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-18811", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-18811/samples/"}