{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM466504": {"DEVELOPMENTAL STAGE": "preterm spontaneous delivery (<34 weeks of gestation)"}}, {"GSM466504": {"DEVELOPMENTAL STAGE": "preterm spontaneous delivery (<34 weeks of gestation)"}}, {"GSM466504": {"DEVELOPMENTAL STAGE": "preterm spontaneous delivery (<34 weeks of gestation)"}}, {"GSM466504": {"DEVELOPMENTAL STAGE": "preterm spontaneous delivery (<34 weeks of gestation)"}}, {"GSM466504": {"DEVELOPMENTAL STAGE": "preterm spontaneous delivery (<34 weeks of gestation)"}}, {"GSM466509": {"DEVELOPMENTAL STAGE": "term spontaneous delivery (38-39 weeks of gestation)"}}, {"GSM466509": {"DEVELOPMENTAL STAGE": "term spontaneous delivery (38-39 weeks of gestation)"}}, {"GSM466509": {"DEVELOPMENTAL STAGE": "term spontaneous delivery (38-39 weeks of gestation)"}}, {"GSM466509": {"DEVELOPMENTAL STAGE": "term spontaneous delivery (38-39 weeks of gestation)"}}, {"GSM466509": {"DEVELOPMENTAL STAGE": "term spontaneous delivery (38-39 weeks of gestation)"}}], "id": 3470, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "We hypothesized that preterm spontaneous labor involves aberrant changes in mRNA expression in the placenta. To test this hypothesis, we...", "geo_gse_id": "E-GEOD-18809", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 10, "tags": ["genome", "placenta"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "differentially-expressed-mrna-transcripts-in-the-p", "geo_id_plat": "E-GEOD-18809_A-AFFY-44", "name": "Differentially expressed mRNA transcripts in the placenta delivered by preterm versus term spontaneous labour", "created": "Sep.15, 2014", "summary": "We hypothesized that preterm spontaneous labor involves aberrant changes in mRNA expression in the placenta. To test this hypothesis, we interrogated the mRNA levels of >50,000 genes and transcript variants using gene expression microarray (Human Genome U133 Plus 2.0 Array, Affymetrix) on 5 placentas collected from preterm spontaneous delivery (<34 weeks of gestation) and another 5 placentas collected from term spontaneous delivery (38-39 weeks). We have identified 229 and 162 genes that were up- or down-regulated, respectively, for more than 3-fold in the preterm placentas compared to the term placentas (Mann-Whitney Rank Sum Test, with multiple testing correction by the Benjamini-Hochberg method, adjusted p-value <= 0.05). Placentas collected from (i) preterm spontaneous delivery (<34 weeks of gestation) and (ii) term spontaneous delivery (38-39 weeks of gestation) were subjected to RNA extraction and hybridization on Affymetrix microarrays. To identify gene expression patterns that are commonly involved in preterm spontaneous labour, we analyzed 5 placentas from each of these 2 groups and tested for any differentially expressed genes by Mann-Whitney Rank Sum Test.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-18809", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-18809/samples/"}