Dataset: Deciphering the Wnt-dependent gene signature in colorectal cancer cells

Microarray-based gene expression data were generated from RNA from Ls174T colorectal carcinoma cell lines in which Wnt-dependent transcriptional activity can be abrogated by inducible overexpression of a dominant-negative form of Tcf4 or siRNA against β-catenin. shRNA against β-catenin, or a dominant-negative Tcf4 transgene, were induced in Ls174T cells for 72 or 24 hours, respectively. Uninduced cells were used as a control. Three replicates per condition.

Species:

human

Samples:

12

Source:

E-GEOD-18560

PubMed:

21914722

Updated:

Dec.12, 2014

Registered:

Sep.15, 2014