{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSE18476GSM460066": {}}, {"GSE18476GSM460067": {}}, {"GSE18476GSM460068": {}}, {"GSE18476GSM460069": {}}, {"GSE18476GSM460070": {}}, {"GSE18476GSM460071": {}}], "id": 3442, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "The PLZF-RARa fusion oncoprotein is overexpressed in the t(11;17) subtype of acute promyelocytic leukemia. Gene expression microarrays...", "geo_gse_id": "E-GEOD-18476", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 6, "tags": ["cell", "leukemia", "line"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-of-human-u937tplzf-rara-in", "geo_id_plat": "E-GEOD-18476_A-AFFY-44", "name": "Transcription profiling of human U937T:PLZF-RARa Inducible Cells", "created": "Sep.15, 2014", "summary": "The PLZF-RARa fusion oncoprotein is overexpressed in the t(11;17) subtype of acute promyelocytic leukemia. Gene expression microarrays were used to identify genes involved in leukemic transformation. We used microarray to detect gene expression changes induced by the PLZF-RARa fusion oncoprotein in the U937 cell line Experiment Overall Design: The U937T:PLZF-RARa cell line was engineered to express PLZF-RARa upon tetracycline removal. PLZF-RARa was induced for 48hr and RNA was extracted and hybridized to Affymetrix HGU133Plus2.0 Chips", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-18476", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-18476/samples/"}