ArrayExpress Uploader0mouseCD4 T cells, pancreas infiltrating0 hrsCD4 T cells, pancreas infiltrating0 hrsCD4 T cells, pancreas infiltrating15 hrsCD4 T cells, pancreas infiltrating15 hrsCD4 T cells, pancreas infiltrating24 hrsCD4 T cells, pancreas infiltrating24 hrsCD4 T cells, pancreas draining lymph node0 hrsCD4 T cells, pancreas draining lymph node0 hrsCD4 T cells, pancreas draining lymph node15 hrsCD4 T cells, pancreas draining lymph node15 hrsCD4 T cells, pancreas draining lymph node24 hrsCD4 T cells, pancreas draining lymph node24 hrs5830arrayexpress_sid6How do Treg cells control an autoimmune lesion? We depleted Foxp3+ Treg cells in autoimmune prone TCR transgenic BDC2.5 mice on the NOD...E-GEOD-18136/profile/8773/arrayexpressuploader212celldiphtherialymphlymph nodepancreasDec.12, 2014FalseE-GEOD-18136_A-AFFY-45punctual-ablation-of-foxp3-t-cells-unleashes-an-auPunctual ablation of Foxp3+ T cells unleashes an autoimmune lesionNov.11, 2014How do Treg cells control an autoimmune lesion? We depleted Foxp3+ Treg cells in autoimmune prone TCR transgenic BDC2.5 mice on the NOD background Kinetic of gene-expression changes in CD4 T cells isolated for pancreas and pancreas draining lymph node (PLN) of Foxp3-DTR.BDC2.5/NOD mice after Treg cell ablation Keywords: T cell activation/ differentiation after Treg depletion timecourse CD4 T cells were isolated from pancreas and PLN at 0, 15 and 24 hours after diphtheria toxin application into 4-6 week old female Foxp3-DTR.BDC2.5/NOD transgenic micehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-18136http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-18136/samples/