Dataset: Punctual ablation of Foxp3+ T cells unleashes an autoimmune lesion
How do Treg cells control an autoimmune lesion? We depleted Foxp3+ Treg cells in autoimmune prone TCR transgenic BDC2.5 mice on the NOD...
How do Treg cells control an autoimmune lesion? We depleted Foxp3+ Treg cells in autoimmune prone TCR transgenic BDC2.5 mice on the NOD background Kinetic of gene-expression changes in CD4 T cells isolated for pancreas and pancreas draining lymph node (PLN) of Foxp3-DTR.BDC2.5/NOD mice after Treg cell ablation Keywords: T cell activation/ differentiation after Treg depletion timecourse CD4 T cells were isolated from pancreas and PLN at 0, 15 and 24 hours after diphtheria toxin application into 4-6 week old female Foxp3-DTR.BDC2.5/NOD transgenic mice
- Species:
- mouse
- Samples:
- 12
- Source:
- E-GEOD-18136
- Updated:
- Dec.12, 2014
- Registered:
- Nov.11, 2014
Factors:
(via ArrayExpress)
| Sample | CELL TYPE | TIME |
|---|---|---|
| GSM453573 | CD4 T cells, pancreas infiltrating | 0 hrs |
| GSM453573 | CD4 T cells, pancreas infiltrating | 0 hrs |
| GSM453575 | CD4 T cells, pancreas infiltrating | 15 hrs |
| GSM453575 | CD4 T cells, pancreas infiltrating | 15 hrs |
| GSM453577 | CD4 T cells, pancreas infiltrating | 24 hrs |
| GSM453577 | CD4 T cells, pancreas infiltrating | 24 hrs |
| GSM453579 | CD4 T cells, pancreas draining lymph node | 0 hrs |
| GSM453579 | CD4 T cells, pancreas draining lymph node | 0 hrs |
| GSM45358 | CD4 T cells, pancreas draining lymph node | 15 hrs |
| GSM45358 | CD4 T cells, pancreas draining lymph node | 15 hrs |
| GSM453583 | CD4 T cells, pancreas draining lymph node | 24 hrs |
| GSM453583 | CD4 T cells, pancreas draining lymph node | 24 hrs |